Accuracy of the New Creatinine-based Equations for Estimating Glomerular Filtration Rate in Koreans
نویسنده : Tae-Dong Jeong , Jinyoung Hong , Woochang Lee , Sail Chun , and Won-Ki Min.
تاریخ انتشار : 1402/02/01
Methods: We analyzed 1,654 Korean patients aged ≥18 years who underwent chromium51-ethylenediamine tetraacetic acid GFR measurements (mGFR). Bias (eGFR–mGFR),
root mean square error (RMSE), and proportion of eGFR within 30% of mGFR (P30) of
the 2009 CKD-EPI, 2021 CKD-EPI, and EFKC equations were compared. The concordance rate between eGFR and mGFR categories was evaluated. Both eGFR and mGFR
categories were classified into six groups: ≥90, 89–60, 59–45, 44–30, 29–15, and <15
mL/min/1.73 m2
.
Results: The median bias (mL/min/1.73 m2
) was 1.8 for the 2009 CKD-EPI equation, 4.8
for the 2021 CKD-EPI equation, and –0.3 for the EKFC equation. The P30 and RMSE were
78.2% and 17.0 for the 2009 CKD-EPI equation, 75.6% and 17.4 for the 2021 CKD-EPI
equation, and 80.0% and 16.7 for the EKFC equation, respectively. The overall GFR category concordance rate between eGFR and mGFR was 63.4% for the 2009 CKD-EPI equation, 60.5% for the 2021 CKD-EPI equation, and 61.0% for the EKFC equation.
Conclusions: Among the three eGFR equations, the EKFC equation had the smallest bias
and highest P30 in Koreans. The 2009 CKD-EPI equation had a lower bias than the 2021
CKD-EPI equation